Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697139 | 0.88 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9696745 | 0.80 | MEN1 (0.34) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL10335300 | 0.79 | PTGS2 (0.33) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL10335301 | 0.79 | PTGS2 (0.33) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL10693357 | 0.77 | HMGCR (0.46) | ALDH1A1KDM4ELMNASMN1; SMN2HMGCR | |
| SCHEMBL6241912 | 0.76 | HMGCR (0.57) | HMGCR | |
| SCHEMBL10679732 | 0.76 | HMGCR (0.57) | HMGCR | |
| SCHEMBL6327616 | 0.76 | HMGCR (0.57) | HMGCR | |
| SCHEMBL9756864 | 0.75 | HMGCR (0.38) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9756865 | 0.75 | HMGCR (0.38) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265640-A2 | Azaindole and indolizine derivatives, processes for their production and their use as pharmaceuticals | SANDOZ AG (CH) | 1988-05-04 | — | — | EP | disclosed |