Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700180 | 0.86 | BRD4 (0.36) | MEN1KMT2ARAB9AESR1KDM4E | |
| SCHEMBL10701783 | 0.86 | KMT2A (0.40) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10695102 | 0.85 | KDM4E (0.38) | CREBBPKDM4EALDH1A1SMYD3HSD17B10 | |
| SCHEMBL10694302 | 0.79 | KDM4E (0.43) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10697092 | 0.76 | CREBBP (0.36) | MEN1KMT2ARAB9ACREBBPESR1 | |
| SCHEMBL10694978 | 0.76 | MEN1 (0.36) | MEN1KMT2ARAB9AESR1KDM4E | |
| SCHEMBL10697214 | 0.75 | ALDH1A1 (0.40) | MEN1KMT2ARAB9ACREBBPKDM4E | |
| SCHEMBL10698133 | 0.72 | BRD4 (0.36) | KMT2AKDM4EALDH1A1HSD17B10BRD4 | |
| SCHEMBL10700985 | 0.70 | KMT2A (0.36) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10697809 | 0.70 | CNR1 (0.39) | MEN1KMT2ARAB9AESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |