Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.43 |
| ▸ | HRH1 | P35367 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL10754715 | 0.94 | HTR2A (0.41) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10694474 | 0.88 | CYP3A4 (0.41) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10759482 | 0.87 | SLC6A3 (0.42) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Hydrochloric Acid SCHEMBL10692827 | 0.86 | SLC6A3 (0.42) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Hydrochloric Acid SCHEMBL10409299 | 0.83 | LMNA (0.43) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Hydrochloric Acid SCHEMBL10695977 | 0.77 | DRD2 (0.42) | HTR2AADRA1ADRD3DRD2TDP1 | |
| Hydrochloric Acid SCHEMBL10570034 | 0.75 | MEN1 (0.38) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| SCHEMBL10689170 | 0.71 | ADRA1A (0.40) | ADRA1ADRD3MEN1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL10770827 | 0.71 | MEN1 (0.35) | HTR2AADRA1AHRH1DRD3OPRK1 | |
| Hydrochloric Acid SCHEMBL10573477 | 0.70 | ABCB1 (0.39) | HTR2AADRA1AHRH1DRD3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |