Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 7/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.42 |
| ▸ | HRH1 | P35367 | 7/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.42 |
| ▸ | HRH2 | P25021 | 5/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD5 | P21918 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10692827 | 0.99 | SLC6A3 (0.42) | SLC6A3OPRK1OPRM1HTR2AADRA1A | |
| SCHEMBL10694474 | 0.92 | CYP3A4 (0.41) | SLC6A3OPRK1OPRM1HTR2AADRA1A | |
| SCHEMBL10691826 | 0.87 | HTR2A (0.43) | SLC6A3OPRK1OPRM1HTR2AADRA1A | |
| Maleic Acid SCHEMBL10754715 | 0.82 | HTR2A (0.41) | SLC6A3OPRK1OPRM1HTR2AADRA1A | |
| SCHEMBL10763371 | 0.80 | HTR1A (0.42) | DRD3DRD4DRD2HTR1AMEN1 | |
| SCHEMBL10694576 | 0.80 | POLB (0.33) | ADRA1AADRA1DHTR7ADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL10409299 | 0.80 | LMNA (0.43) | SLC6A3OPRK1OPRM1HTR2AADRA1A | |
| SCHEMBL10695992 | 0.75 | SCN9A (0.39) | ADRA1AADRA1DHTR7ADRA1BLMNA | |
| Hydrochloric Acid SCHEMBL10570034 | 0.73 | MEN1 (0.38) | SLC6A3OPRK1OPRM1HTR2AADRA1A | |
| SCHEMBL10759620 | 0.72 | DRD2 (0.41) | ADRA1ADRD3DRD4ADRA1DHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212216-A1 | Dihydroquinolinone derivatives, processes for their preparation, medicaments containing them, the use of these medicaments, and intermediates for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |