SCHEMBL10691860

SCHEMBL10691860

CCOCn1nccc1C(=O)c1ccc(OC(Cl)C(=O)O)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RAB9A P51151 3/20 0.33
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
JAK2 O60674 1/20 0.31
TYK2 P29597 1/20 0.31
HSD17B10 Q99714 1/20 0.31
BTK Q06187 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504237 0.89 SMN1; SMN2 (0.43) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL27286017 0.75 KMT2A (0.40) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL9746104 0.73 L3MBTL1 (0.39) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL9506410 0.72 ALDH1A1 (0.48) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL27286783 0.70 HSP90AA1 (0.43) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11455560 0.70 SMN1; SMN2 (0.52) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL9685754 0.69 KMT2A (0.42) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL27293150 0.68 MEN1 (0.33) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL4410366 0.68 GSTP1 (0.45) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11603769 0.68 THRB (0.52) MAPTSMN1; SMN2ALDH1A1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268800-A1 Phenoxyacetic acid derivatives and processes for preparing the same Tanabe Seiyaku Co., Ltd. (JP) 1988-06-01 EP disclosed