Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691860 | 0.89 | MAPT (0.33) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11455560 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4410366 | 0.71 | GSTP1 (0.45) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11603769 | 0.71 | THRB (0.52) | SMN1; SMN2MAPTALDH1A1RAB9AHTT | |
| SCHEMBL11419596 | 0.70 | MAPT (0.49) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9503246 | 0.70 | MEN1 (0.47) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11268947 | 0.69 | HPGD (0.50) | SMN1; SMN2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL11603981 | 0.69 | MAPT (0.38) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9502467 | 0.69 | MEN1 (0.52) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10400883 | 0.69 | MEN1 (0.48) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414931-B1 | HYPOTENSIVE AGENT | TANABE SEIYAKU CO (JP) | 1993-07-14 | — | — | EP | disclosed |
| EP-0414931-A1 | Hypotensive agent | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |