Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130780 | 0.76 | HCAR3 (0.59) | HCAR3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL31721465 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL498268 | 0.74 | TSHR (0.52) | KMT2AMEN1NPC1POLBSMN1; SMN2 | |
| SCHEMBL15574025 | 0.73 | CA12 (0.59) | HCAR3RAB9AHTTALDH1A1PKM | |
| SCHEMBL3529075 | 0.72 | HCAR3 (0.55) | HCAR3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL27845415 | 0.71 | PTPN1 (0.55) | HCAR3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10502222 | 0.71 | HCAR3 (1.00) | HCAR3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL29364242 | 0.71 | TPMT (0.58) | POLBSMN1; SMN2TP53ALDH1A1MAPT | |
| SCHEMBL2723610 | 0.71 | TPMT (0.58) | POLBSMN1; SMN2TP53ALDH1A1MAPT | |
| SCHEMBL7434160 | 0.71 | ALDH1A1 (0.50) | KMT2AMEN1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |