SCHEMBL2723610

SCHEMBL2723610

O=C(O)c1ccc(I)c(I)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 4/20 0.58
TSHR P16473 3/20 0.52
TP53 P04637 1/20 0.52
CA1 P00915 5/20 0.50
CA2 P00918 5/20 0.50
CA12 O43570 4/20 0.50
CA6 P23280 4/20 0.50
CA9 Q16790 4/20 0.50
CA4 P22748 3/20 0.50
CA7 P43166 3/20 0.50
CA14 Q9ULX7 3/20 0.50
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
PTGS2 P35354 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GRIN2D O15399 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2C Q14957 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364242 1.00 TPMT (0.58) TPMTTSHRTP53CA1CA2
SCHEMBL205882 0.83 TPMT (0.56) TPMTTSHRTP53CA1CA2
SCHEMBL30574437 0.81 CA12 (0.64) TPMTTSHRTP53CA1CA2
SCHEMBL566608 0.81 CA12 (0.64) TPMTTSHRTP53CA1CA2
SCHEMBL30329647 0.81 CA12 (0.64) TPMTTSHRTP53CA1CA2
SCHEMBL7803073 0.81 TPMT (0.54) TPMTTSHRTP53CA1CA2
SCHEMBL351139 0.81 CA12 (0.64) TPMTTSHRTP53CA1CA2
SCHEMBL6645457 0.81 TPMT (0.54) TPMTTSHRTP53CA1CA2
SCHEMBL9080711 0.81 KDM4E (0.52) TPMTTSHRTP53CA1CA2
SCHEMBL17816183 0.79 TPMT (0.48) TPMTTSHRTP53CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110974816-B Application of difunctional iodinated carboxylic acid as coxsackievirus inhibitor 湖北工业大学 2023-05-16 CN claimed
CN-111053763-B Application of bifunctional iodine-containing aromatic acid in resisting EV71 virus 湖北工业大学 2021-04-02 CN claimed
CN-111116395-A Multi-iodo aromatic acid compound and application thereof in resisting adenovirus 7 湖北工业大学 2020-05-08 CN claimed
CN-111053763-A Application of bifunctional iodine-containing aromatic acid in resisting EV71 virus 湖北工业大学 2020-04-24 CN claimed
CN-110974816-A Application of bifunctional iodocarboxylic acid as coxsackie virus inhibitor 湖北工业大学 2020-04-10 CN claimed
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 US disclosed
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-19 US disclosed
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-12 US disclosed
US-20260014282-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES FOR USE IN MEDICAL HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-15 US disclosed
US-20250249130-A1 RADIOPAQUE POLYPEPTIDES FOR INJECTABLE COMPOSITIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-08-07 US disclosed
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-02-20 US disclosed
US-12146028-B2 Iodo-functionalized polymers as mass spectrometry calibrants with a mass-defect offset POLYMER FACTORY SWEDEN AB (SE) 2024-11-19 US disclosed
US-9725457-B2 6-amido derivatives of 4, 5-a epoxymorphinans for the treatment of pain SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2017-08-08 US disclosed
EP-2630150-B1 6-AMIDO DERIVATIVES OF 4,5A-EPOXYMORPHINANS FOR TREATMENT OF PAIN MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2017-04-12 EP disclosed
US-20140255308-A1 6-AMIDO DERIVATIVES OF 4, 5-a EPOXYMORPHINANS FOR THE TREATMENT OF PAIN MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2014-09-11 US disclosed
US-20130289060-A1 6-AMIDO DERIVATIVES OF 4, 5-a EPOXYMORPHINANS FOR THE TREATMENT OF PAIN MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2013-10-31 US disclosed
EP-2630150-A2 6-AMIDO DERIVATIVES OF 4,5A-EPOXYMORPHINANS FOR TREATMENT OF PAIN Memorial Sloan-Kettering Cancer Center (US) 2013-08-28 EP disclosed
WO-2012054566-A2 6-AMIDO DERIVATIVES OF 4,5A-EPOXYMORPHINANS FOR TREATMENT OF PAIN MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2012-04-26 WO disclosed
US-7371866-B2 Preparation of aromatic and heteroaromatic carboxylic acids by catalytic ozonolysis DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2008-05-13 US disclosed
US-20030216577-A1 Preparation of aromatic and heteroaromatic carboxylic acids by catalytic ozonolysis DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM HDGF, IAPP, QRFPR TPMT 4779/4885TSHR 189/4885TP53 151/4885
US-20130289060-A1 6-AMIDO DERIVATIVES OF 4, 5-a EPOXYMORPHINANS FOR THE TREATMENT OF PAIN OPRL1, OPRM1, OPRD1 TPMT 1853/4885TSHR 517/4885TP53 4683/4885
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL TPMT 4080/4885TSHR 689/4885TP53 19/4885
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM NPPA, MACF1, IGF1R TPMT 3130/4885TSHR 103/4885TP53 1399/4885
US-20260014282-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES FOR USE IN MEDICAL HYDROGELS IAPP, NPPA, ARG1 TPMT 4779/4885TSHR 288/4885TP53 220/4885
US-20140255308-A1 6-AMIDO DERIVATIVES OF 4, 5-a EPOXYMORPHINANS FOR THE TREATMENT OF PAIN OPRL1, OPRM1, OPRD1 TPMT 1853/4885TSHR 517/4885TP53 4683/4885
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME PAM, CRYAA, COL1A1 TPMT 3261/4885TSHR 3455/4885TP53 1394/4885
US-20250249130-A1 RADIOPAQUE POLYPEPTIDES FOR INJECTABLE COMPOSITIONS IAPP, IGFBP6, NPPA TPMT 4869/4885TSHR 468/4885TP53 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.