Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000050 | 0.96 | ALOX15 (0.46) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| SCHEMBL29882743 | 0.96 | ALOX15 (0.46) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| SCHEMBL11350890 | 0.93 | TYMS (0.49) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| SCHEMBL11731806 | 0.92 | ALOX15 (0.41) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| SCHEMBL1271125 | 0.87 | ALDH1A1 (0.49) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| SCHEMBL8837160 | 0.84 | TDP1 (0.42) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| SCHEMBL617136 | 0.82 | ALDH1A1 (0.56) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| SCHEMBL3544809 | 0.81 | KEAP1 (0.58) | ALOX15TDP1TYMSALDH1A1MAPT | |
| SCHEMBL18301594 | 0.81 | PDK2 (0.44) | ALOX15TDP1TYMSALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28875558 | 0.81 | ALDH1A1 (0.55) | ALOX15TDP1TYMSALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253765-A1 | Diamino-9,10-dihydroanthracenes and polyamide-acid (esters) and polyimides thereof | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | disclosed |