SCHEMBL1000050

SCHEMBL1000050

O=C1OC(=O)c2c1cccc2C(=O)c1cccc2c1C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TYMS P04818 4/20 0.44
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
KEAP1 Q14145 2/20 0.39
NFE2L2 Q16236 1/20 0.39
HNF4A P41235 1/20 0.37
MYC P01106 1/20 0.36
PARP1 P09874 1/20 0.36
HSD17B10 Q99714 2/20 0.35
MAOA P21397 1/20 0.34
LIG1 P18858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29882743 1.00 ALOX15 (0.46) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL10692219 0.96 ALOX15 (0.48) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL11350890 0.89 TYMS (0.49) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL11731806 0.88 ALOX15 (0.41) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL8837160 0.87 TDP1 (0.42) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL1271125 0.87 ALDH1A1 (0.49) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL617136 0.86 ALDH1A1 (0.56) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL3544809 0.84 KEAP1 (0.58) ALOX15TDP1TYMSALDH1A1MAPT
Hydrochloric Acid SCHEMBL28875558 0.84 ALDH1A1 (0.55) ALOX15TDP1TYMSALDH1A1L3MBTL1
SCHEMBL18301594 0.84 PDK2 (0.44) ALOX15TDP1TYMSALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9349584-B2 Method for depositing a film and film deposition apparatus TOKYO ELECTRON LIMITED (JP) 2016-05-24 US claimed
US-20150087158-A1 METHOD FOR DEPOSITING A FILM AND FILM DEPOSITION APPARATUS TOKYO ELECTRON LIMITED (JP) 2015-03-26 US claimed
US-7863463-B2 Method of purifying dianhydrides SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-01-04 US claimed
EP-2114849-A1 METHOD OF PURIFYING DIANHYDRIDES Sabic Innovative Plastics IP B.V. (NL) 2009-11-11 EP claimed
US-7495113-B2 Method of purifying dianhydrides SABIC INNOVATIVE PLASTICS (US) 2009-02-24 US claimed
WO-2008082413-A1 METHOD OF PURIFYING DIANHYDRIDES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-10 WO claimed
US-20070117990-A1 Method of purifying dianhydrides GENERAL ELECTRIC COMPANY (US) 2007-05-24 US claimed
US-20060135791-A1 Method of purifying dianhydrides GENERAL ELECTRIC COMPANY 2006-06-22 US claimed
EP-4346935-A1 COATING FOR MEDICAL DEVICES Smart Reactors Service Limited (IE) 2024-04-10 EP disclosed
WO-2022253780-A1 COATING FOR MEDICAL DEVICES Smart Reactors Service Limited (IE) 2022-12-08 WO disclosed
CN-114656788-A Cyclic imide resin composition, prepreg, copper-clad laminate, and printed circuit board 信越化学工业株式会社 2022-06-24 CN disclosed
CN-114207085-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element JSR株式会社 2022-03-18 CN disclosed
CN-108475822-B Nonaqueous electrolyte solution for secondary battery and secondary battery provided with same 斯泰拉化工公司 2022-03-11 CN disclosed
CN-114174372-A Thermosetting resin composition for light reflection, substrate for mounting optical semiconductor element, and optical semiconductor device 昭和电工材料株式会社 2022-03-11 CN disclosed
US-20060178499-A1 Low dielectric constants organic-soluble polyimides, and method for manufacturing thereof HOME SUN INDUSTRIAL CO,. LTD. (TW) 2006-08-10 US disclosed
EP-1674443-A1 Method of purifying dianhydrides The General Electric Company (US) 2006-06-28 EP disclosed
EP-1611196-A1 RECYCLING AND REDUCTION OF PLASTICS AND NON-PLASTICS MATERIAL Poly-Melt Technologies, Ltd. (BVI) (VG) 2006-01-04 EP disclosed
US-20040235970-A1 Recycling and reduction of plastics and non-plastics material NEXT-TEC, LTD. (GB) 2004-11-25 US disclosed
WO-2004083289-A1 RECYCLING AND REDUCTION OF PLASTICS AND NON-PLASTICS MATERIAL POLY-MELT TECHNOLOGIES, LTD. (BVI) (VG) 2004-09-30 WO disclosed
US-6180008-B1 SEPARATION OF AROMATIC HYDROCARBONS W. R. GRACE & CO.-CONN. 2001-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070117990-A1 Method of purifying dianhydrides CA7, HDHD5, CA2 ALOX15 4790/4885TDP1 1591/4885TYMS 3734/4885
US-20060135791-A1 Method of purifying dianhydrides SAMHD1, TREH, DOHH ALOX15 4090/4885TDP1 2169/4885TYMS 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.