SCHEMBL10692724

SCHEMBL10692724

NC(=O)OC1CCCN(CCCCOc2cccc(C(F)(F)F)c2)C1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 9/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
HTT P42858 1/20 0.49
MEN1 O00255 1/20 0.48
LTA4H P09960 1/20 0.47
EPHX2 P34913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10690170 0.97 KMT2A (0.50) HRH3KMT2AKDM4EALDH1A1LMNA
SCHEMBL10697150 0.94 KDM4E (0.56) HRH3KMT2AKDM4EALDH1A1LMNA
Oxalic Acid SCHEMBL10695599 0.92 KDM4E (0.59) HRH3KMT2AKDM4EALDH1A1LMNA
SCHEMBL10692369 0.88 KMT2A (0.53) HRH3KMT2AKDM4EALDH1A1LMNA
Oxalic Acid SCHEMBL10692238 0.82 KDM4E (0.55) HRH3KMT2AKDM4EALDH1A1LMNA
SCHEMBL10690668 0.81 HRH3 (0.53) HRH3KMT2AKDM4EALDH1A1LMNA
SCHEMBL9532091 0.74 HRH3 (0.50) HRH3KMT2AKDM4EALDH1A1LMNA
SCHEMBL10695808 0.74 KDM4E (0.48) HRH3KMT2AKDM4EALDH1A1LMNA
SCHEMBL9698943 0.72 DRD2 (0.51) HRH3LTA4H
SCHEMBL10696993 0.72 KDM4E (0.54) HRH3KDM4EALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252876-A1 Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds CIBA-GEIGY AG (CH) 1988-01-13 EP claimed