Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.63 |
| ▸ | HTR1D | P28221 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170176 | 0.88 | HTR1B (0.63) | HTR1BHTR1DTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL5115767 | 0.83 | ALDH1A1 (0.47) | HTR1BHTR1DL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10691402 | 0.80 | LMNA (0.54) | HTR1BHTR1DTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL10693763 | 0.79 | ALDH1A1 (0.50) | HTR1BHTR1DTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL11162302 | 0.79 | LMNA (0.52) | HTR1BHTR1DTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL11176181 | 0.79 | TSHR (0.51) | HTR1BHTR1DTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL7877916 | 0.78 | GPR84 (0.47) | HTR1BTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10692922 | 0.77 | HTR1B (0.56) | HTR1BHTR1DCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3297203 | 0.73 | PRMT5 (0.50) | HTR1BHTR1DL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10692155 | 0.72 | SLC2A1 (0.50) | HTR1BALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |