Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23271878 | 0.90 | GPR84 (0.44) | GPR84HTR2AL3MBTL1HTR1BMEN1 | |
| SCHEMBL30003180 | 0.90 | KCNA3 (0.51) | L3MBTL1HTR1BALDH1A1KDM4ETDP1 | |
| SCHEMBL23271651 | 0.90 | KCNA3 (0.51) | L3MBTL1HTR1BALDH1A1KDM4ETDP1 | |
| SCHEMBL10692520 | 0.87 | L3MBTL1 (0.50) | GPR84HTR2AL3MBTL1HTR1BALDH1A1 | |
| SCHEMBL29371827 | 0.87 | TLR8 (0.44) | GPR84HTR2AL3MBTL1HTR1BTDP1 | |
| SCHEMBL5115767 | 0.87 | ALDH1A1 (0.47) | GPR84HTR2AL3MBTL1HTR1BALDH1A1 | |
| SCHEMBL7966951 | 0.87 | TLR8 (0.44) | GPR84HTR2AL3MBTL1HTR1BTDP1 | |
| SCHEMBL10695998 | 0.87 | HTR1B (0.56) | GPR84HTR2AL3MBTL1HTR1BALDH1A1 | |
| SCHEMBL10691171 | 0.87 | HTR1B (0.59) | GPR84HTR2AL3MBTL1HTR1BKDM4E | |
| SCHEMBL10694110 | 0.87 | L3MBTL1 (0.50) | GPR84HTR2AL3MBTL1HTR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031763-A1 | Substituted bis-acridines and related compounds as CCR5 receptor ligands, anti-inflammatory agents and anti-viral agents | SMITHKLINE BEECHAM CORPORATION | 2001-10-18 | — | — | US | claimed |
| US-20130096097-A1 | PHARMACEUTICAL MULTIMERIC PARTICLES, AND MANUFACTURING METHOD FOR SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-04-18 | — | — | US | disclosed |
| US-20130096097-A1 | PHARMACEUTICAL MULTIMERIC PARTICLES, AND MANUFACTURING METHOD FOR SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-04-18 | — | — | US | disclosed |
| US-20010031763-A1 | Substituted bis-acridines and related compounds as CCR5 receptor ligands, anti-inflammatory agents and anti-viral agents | SMITHKLINE BEECHAM CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-6242459-B1 | Substituted bis-acridines and related compounds as CCR5 receptor ligands, anti-inflammatory agents and anti-viral agents | SMITHKLINE BEECHAM CORPORATION | 2001-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031763-A1 | Substituted bis-acridines and related compounds as CCR5 receptor ligands, anti-inflammatory agents and anti-viral agents | CCR5, CCR2, CCR1 | GPR84 35/4885HTR2A 528/4885L3MBTL1 2266/4885 |
| US-20130096097-A1 | PHARMACEUTICAL MULTIMERIC PARTICLES, AND MANUFACTURING METHOD FOR SAME | SAMM50, MRPS27, COG7 | GPR84 3760/4885HTR2A 3922/4885L3MBTL1 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.