Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038231 | 0.80 | HIF1A (0.65) | ALDH1A1HSD17B10LMNAPTGS1MEN1 | |
| SCHEMBL8722784 | 0.79 | KMT2A (0.49) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL3729424 | 0.78 | AOC3 (0.58) | NR3C1CA2CAMK2AAKR1B1ALDH1A1 | |
| SCHEMBL11029986 | 0.77 | ALDH1A1 (0.52) | NR3C1NR1H4CA2CAMK2AAKR1B1 | |
| SCHEMBL28872737 | 0.76 | ANPEP (0.55) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| Chlorphenacyl SCHEMBL7468547 | 0.75 | LMNA (0.66) | NR3C1CA2CAMK2AAKR1B1ALDH1A1 | |
| SCHEMBL202439 | 0.74 | CA2 (0.56) | NR1H4CA2CAMK2AAKR1B1ALDH1A1 | |
| SCHEMBL9274831 | 0.73 | ANPEP (0.45) | NR3C1NR1H4CA2CAMK2AAKR1B1 | |
| SCHEMBL29038250 | 0.73 | CYP3A4 (0.47) | ALDH1A1LMNAPTGS1MEN1KMT2A | |
| SCHEMBL12102412 | 0.73 | NR3C1 (0.50) | NR3C1NR1H4CA2CAMK2AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259185-A1 | Bile acid derivatives, their salts and production thereof | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-03-09 | — | — | EP | disclosed |