SCHEMBL10692354

SCHEMBL10692354

C=CCCC(N)(CC=C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
THRB P10828 1/20 0.35
KMT2A Q03164 1/20 0.35
ODC1 P11926 1/20 0.34
HTT P42858 1/20 0.34
ABCC4 O15439 1/20 0.33
MAPT P10636 1/20 0.33
ARG2 P78540 5/20 0.32
ARG1 P05089 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30651 0.84 ALDH1A1 (0.42) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL9458161 0.82 MEN1 (0.57) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL7993963 0.82 MEN1 (0.57) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL10660318 0.82 ALDH1A1 (0.57) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL9236221 0.80 ODC1 (0.58) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL30787966 0.78 ARG2 (0.41) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL1976687 0.78 ODC1 (0.45) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL10264935 0.77 ARG1 (0.39) ALDH1A1TSHRODC1ARG2ARG1
SCHEMBL9457637 0.77 ALDH1A1 (0.35) ALDH1A1TSHRMEN1CYP1A2THRB
SCHEMBL11087825 0.77 ODC1 (0.48) ALDH1A1TSHRMEN1CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4782148-A THERMAL DECOMPOSITION OF CARBOXY COMPOUND AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1988-11-01 US disclosed