Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19918338 | 0.86 | CA1 (0.54) | CA1CA2MAPK14RAB9AMAPT | |
| SCHEMBL13668076 | 0.86 | CA1 (0.51) | CA1CA2MAPK14RAB9AMAPT | |
| SCHEMBL8973061 | 0.83 | RAB9A (0.61) | CA1CA2RAB9AMAPTGAA | |
| SCHEMBL27660162 | 0.82 | ALOX5 (0.52) | CA1CA2MAPK14RAB9AGAA | |
| SCHEMBL27660160 | 0.82 | ALOX5 (0.52) | CA1CA2MAPK14RAB9AGAA | |
| SCHEMBL10692459 | 0.81 | CA1 (0.48) | CA1CA2MAPK14RAB9AMAPT | |
| SCHEMBL15896069 | 0.80 | ALDH1A1 (0.52) | CA1CA2KYNUL3MBTL1CA12 | |
| SCHEMBL13671125 | 0.78 | MEN1 (0.47) | CA1CA2ACEMEN1KMT2A | |
| SCHEMBL10690963 | 0.78 | CA12 (0.52) | CA1CA2MAPK14RAB9AGAA | |
| SCHEMBL10688730 | 0.78 | CA12 (0.52) | CA1CA2MAPK14RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725687-A | ANTITUMOR AGENTS; SIDE EFFECT REDUCTION; POTENCY | SOUTHERN RESEARCH INSTITUTE (US) | 1988-02-16 | — | — | US | disclosed |