Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786824 | 0.78 | GSK3B (0.38) | TSHR | |
| SCHEMBL10692456 | 0.76 | GRM1 (0.38) | KMT2AMEN1CYP2D6MGLLSMN1; SMN2 | |
| SCHEMBL10692526 | 0.75 | MGLL (0.37) | KMT2AMEN1CYP2D6MGLLSMN1; SMN2 | |
| SCHEMBL3238451 | 0.72 | PGR (0.31) | — | |
| SCHEMBL10691942 | 0.72 | XDH (0.49) | KMT2AMEN1LMNAGAAALDH1A1 | |
| SCHEMBL6493919 | 0.69 | PARP1 (0.42) | KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL28953638 | 0.65 | ALDH1A1 (0.62) | KMT2AMEN1CYP2D6SMN1; SMN2LMNA | |
| SCHEMBL8895195 | 0.65 | SMN1; SMN2 (0.64) | KMT2AMEN1CYP2D6MGLLSMN1; SMN2 | |
| SCHEMBL14067799 | 0.65 | NPSR1 (0.49) | KMT2AMEN1CYP2D6MGLLSMN1; SMN2 | |
| SCHEMBL13268159 | 0.64 | NPC1 (0.46) | KMT2AMEN1CYP2D6MGLLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |