Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.61 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690442 | 0.84 | OPRM1 (0.52) | OPRL1OPRM1OPRK1PLD1OPRD1 | |
| SCHEMBL11031220 | 0.81 | ADRA1A (0.69) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL11033786 | 0.80 | OPRL1 (0.69) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11032271 | 0.80 | ADRA1A (0.80) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL10692072 | 0.78 | OPRM1 (0.54) | OPRL1OPRM1OPRK1PLD1OPRD1 | |
| SCHEMBL11032558 | 0.78 | OPRM1 (0.70) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL11032634 | 0.78 | ADRA1D (0.71) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL10692743 | 0.77 | PLD1 (0.53) | OPRL1OPRM1OPRK1PLD1OPRD1 | |
| SCHEMBL11428029 | 0.77 | ADRA1A (0.83) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11033995 | 0.77 | ADRA1D (0.72) | ADRA1AADRA1DADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791104-A | HYPOTENSIVE, ANTILIPEMIC, ANTIHROMBOTIC, ANTIHYPOXIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1988-12-13 | — | — | US | disclosed |