Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688606 | 0.86 | PDE7A (0.48) | TNKSTNKS2PDE5APDE3BPDE3A | |
| SCHEMBL10693845 | 0.86 | GAA (0.43) | PDE5APDE3BPDE3ADHODHHSD17B10 | |
| SCHEMBL10691722 | 0.84 | MEN1 (0.38) | AMY1APDE5APDE3BPDE3ADHODH | |
| SCHEMBL10688582 | 0.84 | PDE5A (0.38) | AMY1APDE5APDE3BPDE3ADHODH | |
| SCHEMBL10686161 | 0.83 | CDK4 (0.42) | AMY1APDE5APDE3BPDE3ADHODH | |
| SCHEMBL10690944 | 0.83 | EGLN2 (0.39) | PDE5APDE3BPDE3ADHODHPDE2A | |
| SCHEMBL10869682 | 0.82 | KDM4E (0.43) | AMY1ATNKSTNKS2PARP2PDE5A | |
| SCHEMBL10691563 | 0.82 | CA2 (0.42) | PDE5APDE3BPDE3ADHODHPDE2A | |
| SCHEMBL10686472 | 0.82 | PDE5A (0.37) | AMY1APDE5APDE3BPDE3ADHODH | |
| SCHEMBL10685364 | 0.82 | MKNK1 (0.46) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |