Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688606 | 0.82 | PDE7A (0.48) | HTTDHODHPARP1PDE2AFGFR1 | |
| SCHEMBL10692684 | 0.82 | ADORA2B (0.46) | KDM4EHSD17B10HTTSMN1; SMN2DHODH | |
| SCHEMBL10693845 | 0.82 | GAA (0.43) | HSD17B10HTTDHODHPARP1FGFR1 | |
| SCHEMBL10869401 | 0.81 | PIM1 (0.49) | KDM4EHSD17B10HTTSMN1; SMN2NPC1 | |
| SCHEMBL10688582 | 0.80 | PDE5A (0.38) | KDM4EHSD17B10HTTSMN1; SMN2NPC1 | |
| SCHEMBL10690944 | 0.79 | EGLN2 (0.39) | KDM4EHSD17B10HTTSMN1; SMN2DHODH | |
| SCHEMBL10686161 | 0.79 | CDK4 (0.42) | KDM4EHSD17B10HTTSMN1; SMN2DHODH | |
| SCHEMBL10686472 | 0.78 | PDE5A (0.37) | KDM4EHSD17B10HTTSMN1; SMN2DHODH | |
| SCHEMBL10691563 | 0.78 | CA2 (0.42) | KDM4EHSD17B10HTTSMN1; SMN2DHODH | |
| SCHEMBL10691722 | 0.78 | MEN1 (0.38) | KDM4EHSD17B10HTTSMN1; SMN2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184738-A2 | Imidazole derivatives, medicaments containing these compounds, and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1986-06-18 | — | — | EP | disclosed |