Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686161 | 0.90 | CDK4 (0.42) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10691563 | 0.89 | CA2 (0.42) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10689653 | 0.87 | MAPT (0.45) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10691729 | 0.87 | MEN1 (0.41) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10692684 | 0.84 | ADORA2B (0.46) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10688606 | 0.82 | PDE7A (0.48) | PDE5APDE3BPDE3ADHODHPDE2A | |
| SCHEMBL10693845 | 0.82 | GAA (0.43) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10686472 | 0.80 | PDE5A (0.37) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10688582 | 0.80 | PDE5A (0.38) | MEN1KMT2APDE5APDE3BPDE3A | |
| SCHEMBL10690944 | 0.79 | EGLN2 (0.39) | MEN1KMT2APDE5APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0149200-A1 | Novel 2-pnenyl-imidazoles, their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |