Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 1.00 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | GLI1 | P08151 | 1/20 | 0.48 |
| ▸ | GLI2 | P10070 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986567 | 0.81 | ALOX5 (0.67) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL27833465 | 0.81 | ALOX5 (0.67) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL10691751 | 0.80 | GLI1 (0.69) | ALOX5KMT2ASMN1; SMN2GLI1GLI2 | |
| SCHEMBL2853880 | 0.78 | ALOX5 (0.63) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL23923495 | 0.74 | KMT2A (0.61) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL31748975 | 0.74 | KMT2A (0.61) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL12221485 | 0.74 | KMT2A (0.61) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL684282 | 0.74 | MAOB (0.62) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL29216490 | 0.74 | KMT2A (0.58) | ALOX5KMT2ASMN1; SMN2BCHEMAOB | |
| SCHEMBL11922929 | 0.73 | BCHE (0.60) | ALOX5KMT2ASMN1; SMN2BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |