Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | WNT1 | P04628 | 11/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.44 |
| ▸ | CLK2 | P49760 | 6/20 | 0.41 |
| ▸ | CLK3 | P49761 | 5/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066174 | 0.84 | CNR2 (0.48) | DHODH | |
| SCHEMBL14959119 | 0.78 | MGAM (0.57) | MGAMGAASIMGAM2WNT1 | |
| Hydrochloric Acid SCHEMBL10692572 | 0.77 | WNT1 (0.47) | MGAMGAASIMGAM2WNT1 | |
| SCHEMBL10872396 | 0.77 | MPO (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL4061481 | 0.76 | MGAM (0.40) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL14958590 | 0.75 | MGAM (0.50) | MGAMGAASIMGAM2WNT1 | |
| SCHEMBL2307747 | 0.71 | PSMB8 (0.53) | MGAMGAASIMGAM2 | |
| SCHEMBL7702980 | 0.70 | NPC1 (0.55) | GAA | |
| SCHEMBL6582523 | 0.70 | DDAH1 (0.42) | — | |
| SCHEMBL4068221 | 0.69 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252507-A1 | 2-(4-Pyridylaminomethyl)-benzimidazole derivatives having antiviral activity | Maruishi Seiyaku Kabushiki Kaisha (JP) | 1988-01-13 | — | — | EP | disclosed |