Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | C1R | P00736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690287 | 0.79 | F2RL3 (0.32) | HSD17B13MPLKDM4EALDH1A1HPGD | |
| SCHEMBL10696167 | 0.76 | PGK1 (0.32) | — | |
| SCHEMBL10695942 | 0.73 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGD | |
| SCHEMBL10695710 | 0.72 | PDE10A (0.39) | KDM4EALDH1A1HPGDPDE2APDE10A | |
| SCHEMBL10693333 | 0.71 | IDH1 (0.36) | PDE2APDE10ASCN9A | |
| SCHEMBL10696207 | 0.70 | SCN5A (0.32) | — | |
| SCHEMBL10692362 | 0.69 | SCN5A (0.36) | — | |
| SCHEMBL10696194 | 0.69 | PDE2A (0.35) | KDM4EPDE2APDE10ASCN9A | |
| SCHEMBL10691766 | 0.68 | — | — | |
| SCHEMBL10690283 | 0.67 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |