Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 6/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694763 | 0.92 | KDM4E (0.33) | CYP1A2SCN5A | |
| SCHEMBL10695710 | 0.91 | PDE10A (0.39) | CYP1A2SCN5ANPC1RAB9ASCN2A | |
| SCHEMBL10693091 | 0.89 | TRPV1 (0.33) | — | |
| SCHEMBL10694821 | 0.87 | SCN5A (0.36) | IDH1BRD4CYP1A2SCN5ALMNA | |
| SCHEMBL10693958 | 0.86 | SCN5A (0.36) | IDH1CYP1A2SCN5ACYP2C9SMN1; SMN2 | |
| SCHEMBL10696167 | 0.81 | PGK1 (0.32) | — | |
| SCHEMBL10690618 | 0.81 | MEN1 (0.42) | CYP1A2TP53CYP3A4PKMNFKB1 | |
| SCHEMBL10690077 | 0.78 | KMT2A (0.30) | CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL10693113 | 0.77 | KCNH2 (0.36) | IDH1SMN1; SMN2 | |
| SCHEMBL10695942 | 0.76 | ALDH1A1 (0.48) | CYP1A2LMNATP53CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |