Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690077 | 0.93 | KMT2A (0.30) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10691690 | 0.89 | KCNH2 (0.39) | KCNH2SMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL10690618 | 0.82 | MEN1 (0.42) | KDM4E | |
| SCHEMBL10694763 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL10693333 | 0.77 | IDH1 (0.36) | SMN1; SMN2IDH1 | |
| SCHEMBL10695942 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10693958 | 0.76 | SCN5A (0.36) | SMN1; SMN2IDH1KDM4EALDH1A1 | |
| SCHEMBL10694821 | 0.75 | SCN5A (0.36) | SMN1; SMN2IDH1 | |
| SCHEMBL9814421 | 0.72 | NOTUM (0.32) | — | |
| SCHEMBL10603073 | 0.72 | KCNH2 (0.38) | KCNH2SMN1; SMN2KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |