Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694763 | 0.86 | KDM4E (0.33) | SCN5AACSS2KDM4EMAPTALDH1A1 | |
| SCHEMBL10693333 | 0.86 | IDH1 (0.36) | SCN5ACYP2C9IDH1CYP1A2MAPK1 | |
| SCHEMBL10694821 | 0.84 | SCN5A (0.36) | SCN5ACYP2C9CYP2C19ACSS2MAPT | |
| SCHEMBL10693091 | 0.82 | TRPV1 (0.33) | ACSS2KDM4EALDH1A1 | |
| SCHEMBL10690618 | 0.80 | MEN1 (0.42) | CYP2C19KDM4ECYP1A2CNR2MEN1 | |
| SCHEMBL10690077 | 0.77 | KMT2A (0.30) | ALDH1A1CYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10693113 | 0.76 | KCNH2 (0.36) | KDM4EALDH1A1IDH1SMN1; SMN2 | |
| SCHEMBL10695710 | 0.76 | PDE10A (0.39) | SCN5ACYP2C9KDM4EALDH1A1CYP1A2 | |
| SCHEMBL10696194 | 0.76 | PDE2A (0.35) | KDM4EMAPTMEN1KMT2APDE2A | |
| SCHEMBL10695942 | 0.75 | ALDH1A1 (0.48) | CYP2C9CYP2C19KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |