Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693113 | 0.93 | KCNH2 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10690618 | 0.83 | MEN1 (0.42) | KMT2AMEN1CYP1A2 | |
| SCHEMBL10691690 | 0.82 | KCNH2 (0.39) | KMT2AMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10694763 | 0.78 | KDM4E (0.33) | ALDH1A1CYP1A2HPGD | |
| SCHEMBL10693333 | 0.78 | IDH1 (0.36) | LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL10695942 | 0.78 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10693958 | 0.77 | SCN5A (0.36) | KMT2AMEN1ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL10694821 | 0.76 | SCN5A (0.36) | KMT2AMEN1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL10693091 | 0.76 | TRPV1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL9814421 | 0.73 | NOTUM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |