Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 7/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693091 | 0.89 | TRPV1 (0.33) | ACSS2 | |
| SCHEMBL10693333 | 0.87 | IDH1 (0.36) | SCN5AIDH1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10694763 | 0.87 | KDM4E (0.33) | SCN5ACYP1A2ACSS2MAPT | |
| SCHEMBL10693958 | 0.84 | SCN5A (0.36) | SCN5AIDH1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10690618 | 0.79 | MEN1 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL10695710 | 0.78 | PDE10A (0.39) | SCN5ACYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL10690077 | 0.76 | KMT2A (0.30) | CYP1A2KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL10693113 | 0.75 | KCNH2 (0.36) | IDH1SMN1; SMN2 | |
| SCHEMBL10695942 | 0.74 | ALDH1A1 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10601002 | 0.73 | CYP17A1 (0.35) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |