Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 1/20 | 0.45 |
| ▸ | GNB1 | P62873 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.41 |
| ▸ | GSK3B | P49841 | 11/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693463 | 0.85 | ATM (0.42) | GNG2GNB1MAPTTDP1CTNNB1 | |
| SCHEMBL8102062 | 0.84 | ALDH1A1 (0.39) | MAPTTDP1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL10691604 | 0.82 | HPGD (0.44) | GNG2GNB1MAPTCTNNB1WNT3A | |
| SCHEMBL24124966 | 0.81 | RYR2 (0.38) | GSK3BMAPTTDP1CTNNB1WNT3A | |
| SCHEMBL7765239 | 0.81 | ALDH1A1 (0.58) | MAPTTDP1ALDH1A1 | |
| SCHEMBL10779070 | 0.81 | ATM (0.41) | GNG2GNB1MAPTTDP1CTNNB1 | |
| SCHEMBL10688073 | 0.80 | HSD17B3 (0.45) | CTNNB1WNT3A | |
| SCHEMBL4694745 | 0.80 | MAPT (0.47) | MAPTTDP1ALDH1A1 | |
| SCHEMBL24124204 | 0.80 | ALDH1A1 (0.40) | MAPTALDH1A1 | |
| SCHEMBL7084031 | 0.79 | HSD17B3 (0.47) | MAPTCTNNB1WNT3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791104-A | HYPOTENSIVE, ANTILIPEMIC, ANTIHROMBOTIC, ANTIHYPOXIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1988-12-13 | — | — | US | disclosed |
| WO-1987002359-A1 | DIHYDROBENZOTHIOPHENE AND THIOCHROMANE AMINOALCOHOLS | MAGGIONI-WINTHROP S.P.A. (IT) | 1987-04-23 | — | — | WO | disclosed |