Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688073 | 0.96 | HSD17B3 (0.45) | HSD17B3HTR7STSCA2CTNNB1 | |
| SCHEMBL7085094 | 0.92 | HSD17B3 (0.49) | HSD17B3HTR7STSCA2 | |
| SCHEMBL10691604 | 0.91 | HPGD (0.44) | HSD17B3CTNNB1WNT3AMEN1ALDH1A1 | |
| SCHEMBL10693463 | 0.85 | ATM (0.42) | CTNNB1WNT3AALDH1A1MAPTHTT | |
| SCHEMBL25569790 | 0.82 | HPGD (0.47) | HSD17B3STSCTNNB1WNT3AMEN1 | |
| SCHEMBL10779070 | 0.81 | ATM (0.41) | CTNNB1WNT3AALDH1A1MAPTHTT | |
| SCHEMBL7696585 | 0.80 | CTNNB1 (0.57) | HSD17B3HTR7CTNNB1WNT3AALDH1A1 | |
| SCHEMBL10693207 | 0.79 | GNG2 (0.45) | CTNNB1WNT3AALDH1A1MAPT | |
| SCHEMBL8102062 | 0.78 | ALDH1A1 (0.39) | CTNNB1WNT3AALDH1A1MAPTHTT | |
| SCHEMBL4694745 | 0.77 | MAPT (0.47) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044973-B1 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | AMERICAN CYANAMID CO (US) | 2003-10-08 | — | — | EP | disclosed |
| US-6294676-B2 | AS CHEMICAL INTERMEDIATE FOR PREPARING HERBICIDES | AMERICAN CYANAMID COMPANY | 2001-09-25 | — | — | US | disclosed |
| US-20010014745-A1 | PROCESS FOR THE PREPARTION OF 6-(ARYLCARBONYL)-4-OXIMO-DIHYDROBENZOTHIOPYRAN HERBICIDES AND INTERMEDIATES USEFUL THEREIN | DOEHNER JR ROBERT FRANCIS (US) | 2001-08-16 | — | — | US | disclosed |
| EP-0915092-B1 | Process for the preparation of 6-(arylcarbonyl)-4-oximo-dihydrobenzothiopyran herbicides and intermediates useful therein | BASF AG (DE) | 2001-06-13 | — | — | EP | disclosed |
| US-6180797-B1 | MULTISTAGE REACTION AND HYDROLYSIS TO FORM HERBICIDES | AMERICAN CYANAMID CO. | 2001-01-30 | — | — | US | disclosed |
| EP-1044973-A2 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | American Cyanamid Company (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000059898-A2 | PROCESS FOR THE DEHALOGENATION OF THIOCHROMAN AND DIHYDROBENZOTHIOPHENE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |
| US-6008402-A | REACTING CYCLOHEXADIENECARBOXYLATE-4-ONE COMPOUND WITH A BETA MERCAPTOPROPIONIC ACID TO GIVE THIOENOL, CYCLODEHYDRATING THE THIOENOL | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0915092-A1 | Process for the preparation of 6-(arylcarbonyl)-4-oximo-dihydrobenzothiopyran herbicides and intermediates useful therein | American Cyanamid Company (US) | 1999-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014745-A1 | PROCESS FOR THE PREPARTION OF 6-(ARYLCARBONYL)-4-OXIMO-DIHYDROBENZOTHIOPYRAN HERBICIDES AND INTERMEDIATES USEFUL THEREIN | DDT, CYP4X1, CYP2B6 | HSD17B3 693/4885HTR7 1502/4885STS 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.