Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694484 | 0.93 | ALDH1A1 (0.44) | KAT2BPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10351576 | 0.89 | KAT2B (0.54) | KAT2BPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9192086 | 0.87 | KAT2B (0.59) | KAT2BPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9878203 | 0.82 | ALDH1A1 (0.50) | KAT2BPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10694756 | 0.82 | RAPGEF4 (0.40) | KAT2BPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL9877899 | 0.81 | ALDH1A1 (0.62) | KAT2BPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10692288 | 0.81 | POLB (0.44) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10694725 | 0.79 | RAPGEF4 (0.40) | KAT2BPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL10538157 | 0.79 | ALDH1A1 (0.49) | KAT2BPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10597376 | 0.79 | KMT2A (0.45) | KAT2BPOLBALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |