Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694484 | 0.82 | ALDH1A1 (0.44) | POLBALDH1A1SMN1; SMN2NT5ELMNA | |
| SCHEMBL10691575 | 0.82 | RAPGEF4 (0.39) | POLBALDH1A1NT5EMEN1KMT2A | |
| SCHEMBL10693372 | 0.81 | KAT2B (0.53) | POLBALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL10359926 | 0.79 | POLB (0.46) | POLBALDH1A1SMN1; SMN2CYP19A1LMNA | |
| SCHEMBL1717760 | 0.75 | NT5E (0.47) | POLBALDH1A1SMN1; SMN2CYP19A1NT5E | |
| SCHEMBL10389498 | 0.75 | CRHBP (0.44) | POLBALDH1A1SMN1; SMN2CYP19A1LMNA | |
| SCHEMBL10538157 | 0.73 | ALDH1A1 (0.49) | POLBALDH1A1SMN1; SMN2NT5EMEN1 | |
| SCHEMBL10691497 | 0.73 | NT5E (0.57) | POLBALDH1A1NT5ELMNAMEN1 | |
| SCHEMBL10772754 | 0.73 | POLB (0.47) | POLBALDH1A1SMN1; SMN2CYP19A1LMNA | |
| SCHEMBL9817733 | 0.72 | ALDH1A1 (0.51) | POLBALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |