Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | KLK7 | P49862 | 4/20 | 0.58 |
| ▸ | CASR | P41180 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158526 | 0.89 | PKM (0.62) | KMT2ATSHRALDH1A1PKMKLK7 | |
| SCHEMBL4162007 | 0.89 | PKM (0.62) | KMT2ATSHRALDH1A1PKMKLK7 | |
| SCHEMBL4158522 | 0.89 | PKM (0.62) | KMT2ATSHRALDH1A1PKMKLK7 | |
| SCHEMBL10693452 | 0.88 | SMN1; SMN2 (0.57) | KMT2ATSHRKLK7NPC1RAB9A | |
| SCHEMBL10692649 | 0.87 | PKM (0.76) | KMT2ATSHRALDH1A1PKMKLK7 | |
| SCHEMBL9502645 | 0.86 | PKM (0.59) | KMT2ATSHRALDH1A1PKMKLK7 | |
| SCHEMBL10689090 | 0.86 | ALDH1A1 (0.69) | KMT2ATSHRALDH1A1PKMKLK7 | |
| SCHEMBL10693790 | 0.84 | KMT2A (0.60) | KMT2ATSHRALDH1A1PKMRAB9A | |
| SCHEMBL18134893 | 0.82 | PKM (0.67) | KMT2ATSHRALDH1A1PKMKLK7 | |
| SCHEMBL10690937 | 0.81 | CASR (0.62) | KMT2ATSHRALDH1A1PKMCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |