Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697118 | 0.89 | RAB9A (0.37) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL8085332 | 0.83 | ALDH1A1 (0.46) | MAPTALDH1A1RECQLUSP2ALOX15 | |
| SCHEMBL7277024 | 0.80 | ALDH1A1 (0.42) | MAPTALDH1A1RECQLUSP2ALOX15 | |
| SCHEMBL10695963 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1RECQLUSP2ALOX15 | |
| SCHEMBL7267840 | 0.77 | GABRA1 (0.41) | MAPTALDH1A1RECQLMAPK1GAA | |
| SCHEMBL10694147 | 0.76 | ALDH1A1 (0.36) | MAPTALDH1A1RECQLCA12CA1 | |
| SCHEMBL10694946 | 0.76 | PDE4A (0.41) | — | |
| SCHEMBL7371396 | 0.74 | KMT2A (0.43) | MAPTALDH1A1GLAGAAKMT2A | |
| SCHEMBL7377496 | 0.73 | CCNC (0.30) | — | |
| SCHEMBL7376610 | 0.72 | KMT2A (0.43) | MAPTALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |