Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695615 | 0.89 | MAPT (0.40) | ALDH1A1MAPTALOX15CA12CA1 | |
| SCHEMBL7277024 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTRECQLUSP2ALOX15 | |
| SCHEMBL10697122 | 0.85 | MAPT (0.34) | ALDH1A1MAPTRARARARB | |
| SCHEMBL9299692 | 0.83 | MAPT (0.43) | ALDH1A1MAPTRECQLUSP2ALOX15 | |
| SCHEMBL8090525 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTRECQLUSP2ALOX15 | |
| SCHEMBL10693640 | 0.79 | MAPT (0.41) | ALDH1A1MAPTRECQLUSP2ALOX15 | |
| SCHEMBL10697804 | 0.77 | MAPT (0.34) | ALDH1A1MAPT | |
| SCHEMBL10695563 | 0.76 | CA9 (0.36) | ALDH1A1MAPTALOX15CA12CA1 | |
| SCHEMBL7268034 | 0.75 | ALOX5 (0.40) | ALDH1A1MAPTCA12CA9KMT2A | |
| SCHEMBL9559406 | 0.75 | KDM4E (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |