Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688835 | 0.88 | KDM4E (0.40) | KDM4ELMNAALDH1A1TDP1CYP2D6 | |
| SCHEMBL10693121 | 0.86 | NCEH1 (0.33) | LMNANCEH1MAPT | |
| SCHEMBL10696116 | 0.85 | CHEK1 (0.37) | KDM4EALDH1A1NCEH1CYP1A2CYP2D6 | |
| SCHEMBL10690312 | 0.81 | HTR1B (0.51) | KDM4ELMNATDP1CYP1A2CYP2D6 | |
| SCHEMBL10692528 | 0.79 | MAPT (0.49) | HRH3KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10688285 | 0.74 | RAB9A (0.44) | LMNAALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL10694848 | 0.72 | HTR1B (0.61) | HRH3KDM4ELMNAALDH1A1TDP1 | |
| SCHEMBL10693816 | 0.70 | HTR1B (0.51) | HRH3LMNATDP1CYP1A2CYP2D6 | |
| SCHEMBL23089914 | 0.70 | KCNH2 (0.46) | LMNAALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL29371892 | 0.70 | KCNH2 (0.46) | LMNAALDH1A1TDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |