Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692973 | 0.80 | S1PR4 (0.34) | GAANR4A2CYP1A2 | |
| SCHEMBL10693760 | 0.79 | HRH3 (0.43) | MAPTKDM4EHRH3SLC6A4ALDH1A1 | |
| SCHEMBL10694803 | 0.78 | PARP1 (0.42) | KDM4EHTR1B | |
| SCHEMBL10692306 | 0.78 | HTR1B (0.60) | KDM4ECHRNB2CHRNA4HTR1BALDH1A1 | |
| SCHEMBL10690312 | 0.76 | HTR1B (0.51) | KDM4ESLC6A4HTR1BCYP1A2 | |
| SCHEMBL3563997 | 0.75 | ADRA2A (0.50) | MAPTKDM4EGAAMAPK1NR4A2 | |
| SCHEMBL10693171 | 0.74 | SLC6A4 (0.35) | GAAMAPK1HTR1ADRD2DRD4 | |
| SCHEMBL10691905 | 0.73 | L3MBTL1 (0.41) | MAPTHTR2AKCNH2HTR1BCYP1A2 | |
| SCHEMBL10695347 | 0.72 | HTR1B (0.47) | HTR2AHTR1B | |
| SCHEMBL3563207 | 0.72 | HTR7 (0.60) | MAPTNR4A2ACHEHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |