Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696116 | 0.90 | CHEK1 (0.37) | NCEH1DRD4POLBS1PR4MAPT | |
| SCHEMBL10693760 | 0.86 | HRH3 (0.43) | NCEH1LMNAMAPT | |
| SCHEMBL10688835 | 0.84 | KDM4E (0.40) | LMNAMAPTCCR5 | |
| SCHEMBL10691905 | 0.80 | L3MBTL1 (0.41) | POLBLMNAMAPTKCNA3PSEN1 | |
| SCHEMBL10688285 | 0.79 | RAB9A (0.44) | LMNAMAPT | |
| SCHEMBL10692715 | 0.78 | L3MBTL1 (0.40) | KCNA3KCNA5 | |
| SCHEMBL10692973 | 0.77 | S1PR4 (0.34) | POLBS1PR4KCNA3KCNA5 | |
| SCHEMBL23089914 | 0.71 | KCNH2 (0.46) | LMNAKCNA3 | |
| SCHEMBL29371892 | 0.71 | KCNH2 (0.46) | LMNAKCNA3 | |
| SCHEMBL10693771 | 0.70 | HTR1B (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |