SCHEMBL10693942

SCHEMBL10693942

C=C[SiH](OCc1ccccc1[N+](=O)[O-])c1ccccc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 6/20 0.41
HTT P42858 1/20 0.41
MAOB P27338 1/20 0.41
TSHR P16473 3/20 0.40
HPGD P15428 1/20 0.38
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
HTR1A P08908 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
CCR5 P51681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4620386 0.83 HSD17B10 (0.49) HSD17B10SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL11120018 0.82 ALDH1A1 (0.45) MEN1KMT2ANPC1RAB9ACA12
SCHEMBL10389234 0.70 ALDH1A1 (0.53) HSD17B10MEN1KMT2ANPC1RAB9A
SCHEMBL7598113 0.70 HTR1A (0.55) HSD17B10SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL10541184 0.70 ALDH1A1 (0.49) HSD17B10SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL10863915 0.69 HSD17B10 (0.49) HSD17B10SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL4619590 0.69 ALDH1A1 (0.43) MEN1KMT2ANPC1RAB9ACA12
SCHEMBL4618875 0.69 ALDH1A1 (0.43) HSD17B10SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL28292473 0.69 ALDH1A1 (0.48) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL10788778 0.69 ALDH1A1 (0.48) HSD17B10SMN1; SMN2MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282634-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1988-09-21 EP disclosed