Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689455 | 0.84 | ALOX5 (0.62) | ALOX5PTGS1PTGS2MAOB | |
| SCHEMBL7713248 | 0.84 | ALOX5 (0.78) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9707249 | 0.76 | ALOX5 (1.00) | ALOX5PTGS1PTGS2MAOB | |
| SCHEMBL4924177 | 0.76 | MAOB (0.68) | ALOX5PTGS1PTGS2MAOBPPARG | |
| SCHEMBL9512698 | 0.75 | ALOX5 (0.53) | ALOX5PTGS1PTGS2MAOBPPARG | |
| SCHEMBL9707360 | 0.75 | ALOX5 (0.72) | ALOX5PTGS1PTGS2MAOB | |
| SCHEMBL8933773 | 0.75 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL6691879 | 0.75 | MAOB (0.62) | ALOX5PTGS1PTGS2MAOBPPARG | |
| SCHEMBL8332027 | 0.75 | PPARG (0.64) | ALOX5PTGS1PTGS2MAOBPPARG | |
| SCHEMBL28779136 | 0.75 | PPARG (0.60) | ALOX5PTGS1PTGS2MAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |