Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.60 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924177 | 0.78 | MAOB (0.68) | ALOX5MAOBFFAR1 | |
| SCHEMBL17386027 | 0.76 | CYP4F2 (0.59) | MAOBPTGESFFAR1NR4A2 | |
| SCHEMBL6624802 | 0.76 | CYP4F2 (0.59) | MAOBPTGESFFAR1NR4A2 | |
| SCHEMBL670027 | 0.76 | MAOB (0.68) | LTB4RLTB4R2MAOBFFAR1NR4A2 | |
| SCHEMBL23929198 | 0.76 | PTGES (0.55) | LTB4RLTB4R2ALOX5MAOBPTGES | |
| SCHEMBL23929196 | 0.76 | PTGES (0.55) | LTB4RLTB4R2ALOX5MAOBPTGES | |
| SCHEMBL954459 | 0.75 | NR4A2 (0.66) | LTB4RLTB4R2MAOBFFAR1NR4A2 | |
| SCHEMBL9209410 | 0.75 | LTB4R (1.00) | LTB4RLTB4R2ALOX5CYP2D6 | |
| SCHEMBL20905595 | 0.75 | MME (0.59) | LTB4RLTB4R2MAOBPTGESFFAR1 | |
| SCHEMBL1008116 | 0.74 | LTB4R (0.61) | LTB4RLTB4R2MAOBCYP2D6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |