Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929198 | 1.00 | PTGES (0.55) | PTGESMAOBCYP4F2CYP4A11MME | |
| SCHEMBL1317427 | 0.81 | ADRA2B (0.51) | MAOBKMT2A | |
| SCHEMBL1205590 | 0.78 | MAOA (0.39) | MAOBKMT2A | |
| SCHEMBL2167541 | 0.78 | PPARG (0.52) | MAOBNR4A2ALOX5FFAR1NR4A1 | |
| SCHEMBL20905595 | 0.78 | MME (0.59) | PTGESMAOBCYP4F2CYP4A11MME | |
| SCHEMBL16825353 | 0.76 | CYP2D6 (0.55) | PTGESMAOBCYP4F2CYP4A11MME | |
| SCHEMBL17386027 | 0.76 | CYP4F2 (0.59) | PTGESMAOBCYP4F2CYP4A11MME | |
| SCHEMBL6624802 | 0.76 | CYP4F2 (0.59) | PTGESMAOBCYP4F2CYP4A11MME | |
| SCHEMBL10694079 | 0.76 | LTB4R (0.60) | PTGESMAOBNR4A2LTB4RLTB4R2 | |
| SCHEMBL20905349 | 0.76 | MAOB (0.56) | PTGESMAOBCYP4F2CYP4A11MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213358-A1 | BORON-CONTAINING COMPOUNDS AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |