Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 5/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694392 | 0.86 | NPC1 (0.47) | NPC1HTR7OPRL1EHMT2 | |
| SCHEMBL10691444 | 0.84 | ALDH1A1 (0.43) | HTR7OPRL1HTR1ASCN9A | |
| SCHEMBL10692682 | 0.80 | NPC1 (0.47) | NPC1EHMT2 | |
| SCHEMBL10692777 | 0.79 | OPRL1 (0.35) | HTR7OPRL1HTR1ASCN9A | |
| SCHEMBL10692536 | 0.74 | NOTUM (0.41) | NPC1EHMT2 | |
| SCHEMBL10695401 | 0.71 | RAD52 (0.42) | NPC1OPRL1EHMT2 | |
| SCHEMBL10690604 | 0.69 | TDP1 (0.42) | HTR7SCN9A | |
| SCHEMBL10780105 | 0.67 | CNR1 (0.49) | OPRL1SIGMAR1 | |
| SCHEMBL27019600 | 0.67 | EHMT2 (0.44) | SLC6A2EHMT2 | |
| SCHEMBL10694109 | 0.66 | POLB (0.35) | HTR7SLC6A2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0212216-A1 | Dihydroquinolinone derivatives, processes for their preparation, medicaments containing them, the use of these medicaments, and intermediates for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |