Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691597 | 0.82 | ADRA1A (0.39) | RAD52MAPTTSHRADAMTS5ALDH1A1 | |
| SCHEMBL10691351 | 0.82 | GPR55 (0.39) | RAD52EHMT2MAPTLMNAKDM4E | |
| SCHEMBL10692536 | 0.80 | NOTUM (0.41) | RAD52NPC1EHMT2MAPTLMNA | |
| SCHEMBL10693819 | 0.79 | OPRD1 (0.40) | RAD52EHMT2OPRM1OPRK1 | |
| SCHEMBL10694392 | 0.76 | NPC1 (0.47) | RAD52NPC1EHMT2MAPTLMNA | |
| SCHEMBL10694665 | 0.76 | RAD52 (0.36) | RAD52EHMT2MAPTLMNAKDM4E | |
| SCHEMBL10693548 | 0.75 | RAD52 (0.35) | RAD52EHMT2MAPTHTTALDH1A1 | |
| SCHEMBL10691593 | 0.74 | L3MBTL1 (0.42) | NPC1MAPTLMNATSHRADAMTS5 | |
| SCHEMBL10696619 | 0.74 | RAD52 (0.34) | RAD52EHMT2MAPTHTTALDH1A1 | |
| SCHEMBL10691306 | 0.74 | ALDH1A1 (0.41) | RAD52EHMT2MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |