Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9636378 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL1303659 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL584669 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL15021246 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL235159 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL23854749 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL651561 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL82597 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10566608 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL5828494 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118507142-B | Yttrium barium copper oxygen superconducting cable core wire and preparation method and application thereof | 兰州大学 | 2025-02-25 | — | — | CN | claimed |
| CN-118507142-A | Yttrium barium copper oxygen superconducting cable core wire and preparation method and application thereof | 兰州大学 | 2024-08-16 | — | — | CN | claimed |
| CN-114835672-A | Novel rare earth crown ether compound with switchable dielectric response characteristic and preparation method and application thereof | 江西理工大学 | 2022-08-02 | — | — | CN | claimed |
| CN-113480287-A | Preparation method of yttrium-stabilized zirconium dioxide aerogel/fiber composite material | 湖北三江航天红阳机电有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-118507142-B | Yttrium barium copper oxygen superconducting cable core wire and preparation method and application thereof | 兰州大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-119263795-A | High-purity composite rare earth monosilicate ceramic powder and preparation method thereof | 中国科学院合肥物质科学研究院 | 2025-01-07 | — | — | CN | disclosed |
| CN-118507142-A | Yttrium barium copper oxygen superconducting cable core wire and preparation method and application thereof | 兰州大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-114835672-B | Novel rare earth crown ether compound with switchable dielectric response characteristic, and preparation method and application thereof | 江西理工大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114835672-B | Novel rare earth crown ether compound with switchable dielectric response characteristic, and preparation method and application thereof | 江西理工大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117801641-A | Metal organic framework composite coating based on finite field effect and preparation method and application thereof | 东北师范大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-114835672-A | Novel rare earth crown ether compound with switchable dielectric response characteristic and preparation method and application thereof | 江西理工大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114835672-A | Novel rare earth crown ether compound with switchable dielectric response characteristic and preparation method and application thereof | 江西理工大学 | 2022-08-02 | — | — | CN | disclosed |
| US-5500198-A | METAL OXIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1996-03-19 | — | — | US | disclosed |
| US-5468427-A | Process for making ultra-fine ceramic particles | ALFRED UNIVERSITY (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1995002625-A2 | POLYMERIZATION/DEPOLYMERIZATION CATALYST FOR POLYETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5364562-A | Aerosol-plasma deposition of insulating oxide powder | ALFRED UNIVERSITY | 1994-11-15 | — | — | US | disclosed |
| US-5023231-A | Method for preparing a superconductive fiber of film | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| WO-1990015020-A2 | HIGH-TEMPERATURE AEROSOL DECOMPOSITION PROCESS AND PRODUCTS PRODUCED | WORCESTER POLYTECHNIC INSTITUTE (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0341030-A2 | Shaped superconductive materials | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| US-3983077-A | Process for making ceramic resistor materials | TEXAS INSTRUMENTS INCORPORATED (US) | 1976-09-28 | — | — | US | disclosed |