Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PTAFR | P25105 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694493 | 0.79 | PTAFR (0.47) | PTAFRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10693440 | 0.76 | GABRA1 (0.60) | NPC1PTAFRALDH1A1PDE2AMEN1 | |
| SCHEMBL10470823 | 0.75 | PTAFR (0.44) | PTAFR | |
| SCHEMBL10694618 | 0.71 | GABRA1 (0.56) | NPC1PDE2AOXTRAVPR1ABRD4 | |
| SCHEMBL9653808 | 0.69 | PTAFR (0.48) | PTAFRBRD4 | |
| Hydrochloric Acid SCHEMBL9651260 | 0.68 | PTAFR (0.47) | PTAFRBRD4 | |
| SCHEMBL10698677 | 0.67 | GABRA1 (0.56) | OXTRAVPR1ABRD4FGFR1SRC | |
| SCHEMBL11541215 | 0.67 | NPC1 (0.51) | NPC1KDM4EALDH1A1METMEN1 | |
| SCHEMBL259795 | 0.64 | NPC1 (0.77) | NPC1KDM4EALDH1A1SIGMAR1MEN1 | |
| SCHEMBL4420934 | 0.64 | NPC1 (0.65) | NPC1KDM4EALDH1A1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255028-A2 | 1,4-Benzodiazepines, their preparation and use as PAF antagonists | BOEHRINGER INGELHEIM KG (DE) | 1988-02-03 | — | — | EP | disclosed |