SCHEMBL10694492

SCHEMBL10694492

NCCc1ccc([N+](=O)[O-])c(N)c1S(=O)(=O)CCS(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
MAPT P10636 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALOX15 P16050 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
GAA P10253 2/20 0.31
CYP2D6 P10635 1/20 0.31
NSD2 O96028 1/20 0.31
PLCG1 P19174 1/20 0.31
DNMT1 P26358 1/20 0.31
CASP6 P55212 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693379 0.93 APP (0.33) ALDH1A1MAPTF2PRSS1PRSS2
SCHEMBL10692298 0.81 FBP1 (0.32) ALDH1A1MAPTALOX15MEN1KMT2A
SCHEMBL10630338 0.80 CA2 (0.37) ALDH1A1MAPTF2PRSS1PRSS2
SCHEMBL10636690 0.74 TXNRD1 (0.41) ALDH1A1ALOX15CYP3A4KMT2ARAB9A
SCHEMBL9820277 0.67 ALDH1A1 (0.46) ALDH1A1MAPTTDP1ALOX15CYP3A4
SCHEMBL3192229 0.65 CA12 (0.49) ALDH1A1MAPTTDP1ALOX15CYP3A4
SCHEMBL8992757 0.64 TSHR (0.42) ALDH1A1MAPTTDP1ALOX15CYP3A4
SCHEMBL16969066 0.64 SNCA (0.46) ALDH1A1MAPTTDP1ALOX15CYP3A4
SCHEMBL1477561 0.64 ALDH1A1 (0.55) ALDH1A1F2PRSS1PRSS2PRSS3
SCHEMBL7784575 0.63 CYP1A2 (0.58) ALDH1A1MAPTTDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4785099-A FIBER-REACTIVE DYES FOR CELLULOSE HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-15 US disclosed