Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694492 | 0.93 | ALDH1A1 (0.33) | ALDH1A1MAPTF2PRSS1PRSS2 | |
| SCHEMBL10692298 | 0.80 | FBP1 (0.32) | ALDH1A1MAPTTXNRD1MEN1RAB9A | |
| SCHEMBL10630338 | 0.78 | CA2 (0.37) | ALDH1A1MAPTF2PRSS1PRSS2 | |
| SCHEMBL10636690 | 0.72 | TXNRD1 (0.41) | ALDH1A1TXNRD1RAB9AKMT2AGAA | |
| SCHEMBL27964024 | 0.64 | ALDH1A1 (0.58) | KAT2BALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL3192229 | 0.64 | CA12 (0.49) | ALDH1A1MAPTNSD2GAAPLCG1 | |
| SCHEMBL10694766 | 0.63 | APP (0.35) | APP | |
| SCHEMBL5170316 | 0.63 | APP (0.48) | APPALDH1A1MAPTGAA | |
| SCHEMBL4086162 | 0.63 | ATM (0.53) | KAT2BALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1477561 | 0.62 | ALDH1A1 (0.55) | ALDH1A1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |