Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918371 | 0.84 | FPR1 (0.52) | FPR1ALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL10690887 | 0.84 | L3MBTL1 (0.64) | ALDH1A1HPGDL3MBTL1POLBATM | |
| SCHEMBL10694549 | 0.82 | SMN1; SMN2 (0.56) | FPR1ALDH1A1HPGDL3MBTL1POLB | |
| SCHEMBL10693682 | 0.75 | L3MBTL1 (0.50) | ALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL10691682 | 0.75 | NPC1 (0.53) | ALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL10690219 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HPGDL3MBTL1POLBLMNA | |
| SCHEMBL10690936 | 0.72 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL29559437 | 0.72 | ALDH1A1 (0.49) | FPR1ALDH1A1HPGDATM | |
| SCHEMBL22897824 | 0.72 | ALDH1A1 (0.49) | FPR1ALDH1A1HPGDATM | |
| SCHEMBL10692512 | 0.72 | HDAC3 (0.63) | ALDH1A1HPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |